Physical Properties | | | |
Molecular Weight: 286.412 g/mol | logS: -4.2749 | SlogP: 4.3288 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0172481 | Sterimol/B1: 2.18685 | Sterimol/B2: 2.55806 | Sterimol/B3: 3.31289 |
Sterimol/B4: 5.02072 | Sterimol/L: 22.6956 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 630.243 | Positive charged surface: 466.226 | Negative charged surface: 164.017 | Volume: 308.875 |
Hydrophobic surface: 408.506 | Hydrophilic surface: 221.737 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |