Physical Properties | | | |
Molecular Weight: 320.473 g/mol | logS: -4.87692 | SlogP: 4.0367 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.223955 | Sterimol/B1: 2.46899 | Sterimol/B2: 3.36911 | Sterimol/B3: 4.94765 |
Sterimol/B4: 6.17106 | Sterimol/L: 13.0547 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 505.74 | Positive charged surface: 335.461 | Negative charged surface: 170.279 | Volume: 329.25 |
Hydrophobic surface: 361.029 | Hydrophilic surface: 144.711 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |