Physical Properties | | | |
Molecular Weight: 351.156 g/mol | logS: -3.54269 | SlogP: 2.3298 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0208187 | Sterimol/B1: 2.09719 | Sterimol/B2: 3.4547 | Sterimol/B3: 4.41524 |
Sterimol/B4: 6.02109 | Sterimol/L: 13.9287 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 503.863 | Positive charged surface: 252.32 | Negative charged surface: 251.543 | Volume: 271.375 |
Hydrophobic surface: 286.686 | Hydrophilic surface: 217.177 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |