Physical Properties | | | |
Molecular Weight: 412.442 g/mol | logS: -3.84419 | SlogP: 2.98897 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.16554 | Sterimol/B1: 2.0465 | Sterimol/B2: 5.18246 | Sterimol/B3: 5.83741 |
Sterimol/B4: 8.61258 | Sterimol/L: 16.8914 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 685.378 | Positive charged surface: 491.179 | Negative charged surface: 189.163 | Volume: 387.75 |
Hydrophobic surface: 558.161 | Hydrophilic surface: 127.217 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |