Physical Properties | | | |
Molecular Weight: 379.844 g/mol | logS: -3.8285 | SlogP: 2.5346 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0995676 | Sterimol/B1: 2.17801 | Sterimol/B2: 3.45868 | Sterimol/B3: 5.46224 |
Sterimol/B4: 8.05669 | Sterimol/L: 18.1189 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 631.332 | Positive charged surface: 352.978 | Negative charged surface: 273.066 | Volume: 347.25 |
Hydrophobic surface: 425.22 | Hydrophilic surface: 206.112 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |