Physical Properties | | | |
Molecular Weight: 396.535 g/mol | logS: -4.16066 | SlogP: 1.5525 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0390241 | Sterimol/B1: 3.27988 | Sterimol/B2: 3.52658 | Sterimol/B3: 3.61015 |
Sterimol/B4: 8.54409 | Sterimol/L: 21.7687 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 722.372 | Positive charged surface: 526.564 | Negative charged surface: 195.808 | Volume: 408.75 |
Hydrophobic surface: 614.822 | Hydrophilic surface: 107.55 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 4 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |