Physical Properties | | | |
Molecular Weight: 375.449 g/mol | logS: -3.35046 | SlogP: 1.3141 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.031782 | Sterimol/B1: 2.96682 | Sterimol/B2: 3.1953 | Sterimol/B3: 3.38026 |
Sterimol/B4: 6.53978 | Sterimol/L: 19.8916 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 638.019 | Positive charged surface: 407.19 | Negative charged surface: 230.829 | Volume: 339.75 |
Hydrophobic surface: 495.552 | Hydrophilic surface: 142.467 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |