Physical Properties | | | |
Molecular Weight: 375.462 g/mol | logS: -2.15702 | SlogP: 0.9917 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0852195 | Sterimol/B1: 2.29469 | Sterimol/B2: 3.71162 | Sterimol/B3: 3.78501 |
Sterimol/B4: 10.4232 | Sterimol/L: 17.8304 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 698.236 | Positive charged surface: 599.923 | Negative charged surface: 98.3125 | Volume: 375.625 |
Hydrophobic surface: 560.805 | Hydrophilic surface: 137.431 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 7 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |