Physical Properties | | | |
Molecular Weight: 360.454 g/mol | logS: -2.38834 | SlogP: 1.4974 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0728405 | Sterimol/B1: 2.097 | Sterimol/B2: 2.5269 | Sterimol/B3: 5.58737 |
Sterimol/B4: 7.50568 | Sterimol/L: 17.8235 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 644.381 | Positive charged surface: 463.177 | Negative charged surface: 181.204 | Volume: 362.125 |
Hydrophobic surface: 484.92 | Hydrophilic surface: 159.461 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |