Physical Properties | | | |
Molecular Weight: 424.542 g/mol | logS: -1.0108 | SlogP: 0.5537 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.069728 | Sterimol/B1: 2.06561 | Sterimol/B2: 3.78875 | Sterimol/B3: 4.88281 |
Sterimol/B4: 7.95012 | Sterimol/L: 20.8543 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 695.507 | Positive charged surface: 568.954 | Negative charged surface: 126.553 | Volume: 414 |
Hydrophobic surface: 561.83 | Hydrophilic surface: 133.677 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 7 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 0 | |