Physical Properties | | | |
Molecular Weight: 375.222 g/mol | logS: -6.04198 | SlogP: 4.5574 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0226146 | Sterimol/B1: 2.54779 | Sterimol/B2: 4.02244 | Sterimol/B3: 4.15479 |
Sterimol/B4: 7.16579 | Sterimol/L: 17.7047 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 583.785 | Positive charged surface: 310.43 | Negative charged surface: 273.356 | Volume: 308.5 |
Hydrophobic surface: 432.458 | Hydrophilic surface: 151.327 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |