Physical Properties | | | |
Molecular Weight: 393.443 g/mol | logS: -6.12494 | SlogP: 4.437 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0349239 | Sterimol/B1: 2.57285 | Sterimol/B2: 3.29334 | Sterimol/B3: 4.30289 |
Sterimol/B4: 7.81614 | Sterimol/L: 20.7361 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 689.189 | Positive charged surface: 453.895 | Negative charged surface: 235.293 | Volume: 375 |
Hydrophobic surface: 485.369 | Hydrophilic surface: 203.82 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |