Physical Properties | | | |
Molecular Weight: 398.463 g/mol | logS: -3.89405 | SlogP: 2.95547 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0496516 | Sterimol/B1: 3.33101 | Sterimol/B2: 3.98422 | Sterimol/B3: 5.03401 |
Sterimol/B4: 7.4653 | Sterimol/L: 18.4974 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 677.187 | Positive charged surface: 463.318 | Negative charged surface: 211.117 | Volume: 383.625 |
Hydrophobic surface: 452.851 | Hydrophilic surface: 224.336 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |