Physical Properties | | | |
Molecular Weight: 372.464 g/mol | logS: -5.54569 | SlogP: 5.2558 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.330488 | Sterimol/B1: 2.45043 | Sterimol/B2: 3.2105 | Sterimol/B3: 5.43586 |
Sterimol/B4: 8.3409 | Sterimol/L: 13.2787 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 585.55 | Positive charged surface: 338.358 | Negative charged surface: 236.381 | Volume: 365.875 |
Hydrophobic surface: 486.02 | Hydrophilic surface: 99.53 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 3 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |