Physical Properties | | | |
Molecular Weight: 253.298 g/mol | logS: -0.59501 | SlogP: -0.7878 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.131156 | Sterimol/B1: 3.00634 | Sterimol/B2: 3.84578 | Sterimol/B3: 5.07998 |
Sterimol/B4: 6.13713 | Sterimol/L: 12.2442 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 462.127 | Positive charged surface: 311.874 | Negative charged surface: 150.252 | Volume: 243.25 |
Hydrophobic surface: 282.034 | Hydrophilic surface: 180.093 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |