Physical Properties | | | |
Molecular Weight: 376.436 g/mol | logS: -4.07737 | SlogP: 3.6567 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.186427 | Sterimol/B1: 2.83027 | Sterimol/B2: 3.07535 | Sterimol/B3: 4.70002 |
Sterimol/B4: 7.46923 | Sterimol/L: 14.0624 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 531.098 | Positive charged surface: 297.043 | Negative charged surface: 234.054 | Volume: 337.375 |
Hydrophobic surface: 409.805 | Hydrophilic surface: 121.293 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |