Physical Properties | | | |
Molecular Weight: 284.244 g/mol | logS: 0.34022 | SlogP: -3.1563 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.111114 | Sterimol/B1: 2.64142 | Sterimol/B2: 2.75965 | Sterimol/B3: 4.1275 |
Sterimol/B4: 6.56018 | Sterimol/L: 13.1558 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 453.28 | Positive charged surface: 253.695 | Negative charged surface: 199.586 | Volume: 237 |
Hydrophobic surface: 204.862 | Hydrophilic surface: 248.418 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 3 | Basic groups: 1 |
Chiral centers: 5 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |