Physical Properties | | | |
Molecular Weight: 323.345 g/mol | logS: -1.50959 | SlogP: -0.1104 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0566298 | Sterimol/B1: 2.13184 | Sterimol/B2: 2.8843 | Sterimol/B3: 5.4571 |
Sterimol/B4: 5.78697 | Sterimol/L: 19.0958 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 586.429 | Positive charged surface: 382.069 | Negative charged surface: 199.351 | Volume: 300.75 |
Hydrophobic surface: 345.212 | Hydrophilic surface: 241.217 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 5 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |