Physical Properties | | | |
Molecular Weight: 579.356 g/mol | logS: -8.80301 | SlogP: 6.7649 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0865949 | Sterimol/B1: 3.29986 | Sterimol/B2: 3.62475 | Sterimol/B3: 5.24527 |
Sterimol/B4: 10.3302 | Sterimol/L: 17.9854 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 806.044 | Positive charged surface: 364.381 | Negative charged surface: 430.889 | Volume: 497.75 |
Hydrophobic surface: 774.014 | Hydrophilic surface: 32.03 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 1 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 0 | Violations of Lipinski's rule: 2 | Oprea's lead like rule: 0 | |