Physical Properties | | | |
Molecular Weight: 413.473 g/mol | logS: -7.34594 | SlogP: 5.24967 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.119994 | Sterimol/B1: 2.41587 | Sterimol/B2: 4.22148 | Sterimol/B3: 6.4751 |
Sterimol/B4: 7.14214 | Sterimol/L: 18.7618 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 691.164 | Positive charged surface: 408.049 | Negative charged surface: 283.115 | Volume: 395 |
Hydrophobic surface: 569.547 | Hydrophilic surface: 121.617 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |