Physical Properties | | | |
Molecular Weight: 280.324 g/mol | logS: -1.19189 | SlogP: 1.77252 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.260165 | Sterimol/B1: 2.40974 | Sterimol/B2: 4.81646 | Sterimol/B3: 5.86631 |
Sterimol/B4: 6.09528 | Sterimol/L: 11.2361 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 498.907 | Positive charged surface: 363.012 | Negative charged surface: 135.895 | Volume: 270.25 |
Hydrophobic surface: 285.248 | Hydrophilic surface: 213.659 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |