Physical Properties | | | |
Molecular Weight: 377.437 g/mol | logS: -3.32053 | SlogP: 1.9508 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.108095 | Sterimol/B1: 3.61968 | Sterimol/B2: 4.07614 | Sterimol/B3: 5.33465 |
Sterimol/B4: 7.43301 | Sterimol/L: 15.6924 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 658.999 | Positive charged surface: 447.519 | Negative charged surface: 211.48 | Volume: 364.375 |
Hydrophobic surface: 509.084 | Hydrophilic surface: 149.915 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |