Physical Properties | | | |
Molecular Weight: 410.514 g/mol | logS: -6.54183 | SlogP: 5.2988 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.124358 | Sterimol/B1: 3.25188 | Sterimol/B2: 3.49754 | Sterimol/B3: 6.36396 |
Sterimol/B4: 8.23174 | Sterimol/L: 17.7328 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 687.013 | Positive charged surface: 481.406 | Negative charged surface: 205.607 | Volume: 401 |
Hydrophobic surface: 512.089 | Hydrophilic surface: 174.924 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |