Physical Properties | | | |
Molecular Weight: 414.461 g/mol | logS: -4.85659 | SlogP: 3.91764 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.227614 | Sterimol/B1: 2.55473 | Sterimol/B2: 3.66283 | Sterimol/B3: 6.597 |
Sterimol/B4: 6.98597 | Sterimol/L: 14.9482 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 588.471 | Positive charged surface: 374.598 | Negative charged surface: 213.874 | Volume: 389.875 |
Hydrophobic surface: 435.359 | Hydrophilic surface: 153.112 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |