Physical Properties | | | |
Molecular Weight: 428 g/mol | logS: -6.97114 | SlogP: 4.4641 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.132741 | Sterimol/B1: 4.95789 | Sterimol/B2: 5.56567 | Sterimol/B3: 6.00213 |
Sterimol/B4: 8.82096 | Sterimol/L: 19.0154 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 777.187 | Positive charged surface: 510.13 | Negative charged surface: 256.419 | Volume: 438.25 |
Hydrophobic surface: 659.286 | Hydrophilic surface: 117.901 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |