Physical Properties | | | |
Molecular Weight: 396.447 g/mol | logS: -3.08663 | SlogP: 2.13697 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0826289 | Sterimol/B1: 2.23959 | Sterimol/B2: 2.60972 | Sterimol/B3: 5.5095 |
Sterimol/B4: 10.5162 | Sterimol/L: 16.9579 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 656.637 | Positive charged surface: 456.55 | Negative charged surface: 197.542 | Volume: 372.625 |
Hydrophobic surface: 505.868 | Hydrophilic surface: 150.769 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |