Physical Properties | | | |
Molecular Weight: 375.384 g/mol | logS: -5.16313 | SlogP: 4.0936 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0360998 | Sterimol/B1: 2.14384 | Sterimol/B2: 2.57724 | Sterimol/B3: 3.71617 |
Sterimol/B4: 9.18316 | Sterimol/L: 17.6519 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 604.496 | Positive charged surface: 321.189 | Negative charged surface: 278.398 | Volume: 338.25 |
Hydrophobic surface: 414.686 | Hydrophilic surface: 189.81 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |