Physical Properties | | | |
Molecular Weight: 372.387 g/mol | logS: -4.74617 | SlogP: 2.81597 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.203238 | Sterimol/B1: 3.54519 | Sterimol/B2: 4.0713 | Sterimol/B3: 4.1563 |
Sterimol/B4: 8.38843 | Sterimol/L: 12.3982 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 600.226 | Positive charged surface: 309.673 | Negative charged surface: 290.553 | Volume: 336.5 |
Hydrophobic surface: 381.16 | Hydrophilic surface: 219.066 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 3 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |