Physical Properties | | | |
Molecular Weight: 314.32 g/mol | logS: -4.00226 | SlogP: 2.2216 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.00985691 | Sterimol/B1: 2.22777 | Sterimol/B2: 2.24759 | Sterimol/B3: 3.13853 |
Sterimol/B4: 6.132 | Sterimol/L: 19.5302 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 552.644 | Positive charged surface: 278.291 | Negative charged surface: 274.354 | Volume: 283.375 |
Hydrophobic surface: 345.633 | Hydrophilic surface: 207.011 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |