Physical Properties | | | |
Molecular Weight: 424.588 g/mol | logS: -9.37946 | SlogP: 7.5069 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0480837 | Sterimol/B1: 2.42255 | Sterimol/B2: 3.56802 | Sterimol/B3: 3.90167 |
Sterimol/B4: 9.79344 | Sterimol/L: 15.4799 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 725.74 | Positive charged surface: 437.627 | Negative charged surface: 288.112 | Volume: 447.5 |
Hydrophobic surface: 596.489 | Hydrophilic surface: 129.251 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |