Physical Properties | | | |
Molecular Weight: 431.872 g/mol | logS: -4.82232 | SlogP: 3.4118 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.304754 | Sterimol/B1: 3.1414 | Sterimol/B2: 4.02918 | Sterimol/B3: 6.10941 |
Sterimol/B4: 8.82765 | Sterimol/L: 15.6409 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 658.853 | Positive charged surface: 411.695 | Negative charged surface: 247.159 | Volume: 389.125 |
Hydrophobic surface: 510.532 | Hydrophilic surface: 148.321 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |