Physical Properties | | | |
Molecular Weight: 410.45 g/mol | logS: -2.30583 | SlogP: -0.2507 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.142202 | Sterimol/B1: 2.56014 | Sterimol/B2: 4.07608 | Sterimol/B3: 6.76813 |
Sterimol/B4: 7.40682 | Sterimol/L: 16.3948 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 640.096 | Positive charged surface: 455.414 | Negative charged surface: 184.682 | Volume: 382 |
Hydrophobic surface: 438.585 | Hydrophilic surface: 201.511 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |