Physical Properties | | | |
Molecular Weight: 326.396 g/mol | logS: -2.56646 | SlogP: 3.2142 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.217814 | Sterimol/B1: 2.66891 | Sterimol/B2: 5.19871 | Sterimol/B3: 5.45933 |
Sterimol/B4: 6.89117 | Sterimol/L: 13.6224 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 541.285 | Positive charged surface: 407.597 | Negative charged surface: 133.688 | Volume: 318.375 |
Hydrophobic surface: 455.531 | Hydrophilic surface: 85.754 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |