Physical Properties | | | |
Molecular Weight: 374.477 g/mol | logS: -4.31924 | SlogP: 3.9048 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.068421 | Sterimol/B1: 2.66178 | Sterimol/B2: 4.82513 | Sterimol/B3: 4.90552 |
Sterimol/B4: 5.0161 | Sterimol/L: 19.0326 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 615.446 | Positive charged surface: 427.556 | Negative charged surface: 187.89 | Volume: 362.25 |
Hydrophobic surface: 427.371 | Hydrophilic surface: 188.075 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 6 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |