Physical Properties | | | |
Molecular Weight: 511.639 g/mol | logS: -4.89511 | SlogP: 3.18592 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.100374 | Sterimol/B1: 2.29981 | Sterimol/B2: 2.56467 | Sterimol/B3: 7.86772 |
Sterimol/B4: 13.0966 | Sterimol/L: 20.9383 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 897.538 | Positive charged surface: 658.389 | Negative charged surface: 239.148 | Volume: 517.625 |
Hydrophobic surface: 637.996 | Hydrophilic surface: 259.542 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |