Physical Properties | | | |
Molecular Weight: 365.389 g/mol | logS: -3.96382 | SlogP: 1.9728 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0468525 | Sterimol/B1: 3.39986 | Sterimol/B2: 3.73889 | Sterimol/B3: 4.59911 |
Sterimol/B4: 5.50317 | Sterimol/L: 20.5617 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 632.75 | Positive charged surface: 415.634 | Negative charged surface: 211.993 | Volume: 338.875 |
Hydrophobic surface: 501.584 | Hydrophilic surface: 131.166 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |