Physical Properties | | | |
Molecular Weight: 510.54 g/mol | logS: -8.42058 | SlogP: 6.19907 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0177917 | Sterimol/B1: 3.39665 | Sterimol/B2: 3.72509 | Sterimol/B3: 4.27161 |
Sterimol/B4: 7.54968 | Sterimol/L: 25.6555 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 805.38 | Positive charged surface: 454.678 | Negative charged surface: 345.166 | Volume: 445.25 |
Hydrophobic surface: 571.369 | Hydrophilic surface: 234.011 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 0 | Violations of Lipinski's rule: 2 | Oprea's lead like rule: 0 | |