Physical Properties | | | |
Molecular Weight: 564.642 g/mol | logS: -7.65671 | SlogP: 4.6106 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.228705 | Sterimol/B1: 2.08601 | Sterimol/B2: 5.23897 | Sterimol/B3: 7.14774 |
Sterimol/B4: 12.3306 | Sterimol/L: 17.7989 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 872.282 | Positive charged surface: 522.456 | Negative charged surface: 349.826 | Volume: 503.625 |
Hydrophobic surface: 699.914 | Hydrophilic surface: 172.368 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 7 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |