Physical Properties | | | |
Molecular Weight: 387.372 g/mol | logS: -4.2523 | SlogP: 1.5831 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0703775 | Sterimol/B1: 2.54703 | Sterimol/B2: 3.03476 | Sterimol/B3: 3.21472 |
Sterimol/B4: 10.6361 | Sterimol/L: 14.9874 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 589.791 | Positive charged surface: 286.804 | Negative charged surface: 302.987 | Volume: 315.625 |
Hydrophobic surface: 257.58 | Hydrophilic surface: 332.211 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 5 | Hydrogen bond acceptors: 7 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |