Physical Properties | | | |
Molecular Weight: 410.45 g/mol | logS: -2.40749 | SlogP: 0.2195 | Reactive groups: 1 |
| | | |
Topological Properties | | | |
Globularity: 0.101082 | Sterimol/B1: 2.55433 | Sterimol/B2: 3.80881 | Sterimol/B3: 5.30495 |
Sterimol/B4: 7.5475 | Sterimol/L: 17.4768 | | | |
| | | |
Surface and Volume Properties | | | |
Accessible surface: 659.5 | Positive charged surface: 482.761 | Negative charged surface: 176.739 | Volume: 385.5 |
Hydrophobic surface: 458.835 | Hydrophilic surface: 200.665 | | |
| | | |
Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 1 |
Chiral centers: 1 | | | |
| | | |
Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |