Physical Properties | | | |
Molecular Weight: 344.388 g/mol | logS: -2.40219 | SlogP: -0.68808 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.125705 | Sterimol/B1: 1.9779 | Sterimol/B2: 3.24389 | Sterimol/B3: 4.09299 |
Sterimol/B4: 10.5193 | Sterimol/L: 13.7861 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 572.7 | Positive charged surface: 367.02 | Negative charged surface: 205.68 | Volume: 303 |
Hydrophobic surface: 379.338 | Hydrophilic surface: 193.362 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |