Physical Properties | | | |
Molecular Weight: 436.536 g/mol | logS: -6.82446 | SlogP: 5.077 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.187621 | Sterimol/B1: 4.15424 | Sterimol/B2: 4.43066 | Sterimol/B3: 5.94765 |
Sterimol/B4: 8.34201 | Sterimol/L: 17.0978 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 714.489 | Positive charged surface: 468.023 | Negative charged surface: 240.682 | Volume: 404.375 |
Hydrophobic surface: 547.499 | Hydrophilic surface: 166.99 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 1 | |