Physical Properties | | | |
Molecular Weight: 432.548 g/mol | logS: -5.30765 | SlogP: 5.0422 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0874229 | Sterimol/B1: 2.86943 | Sterimol/B2: 3.75048 | Sterimol/B3: 5.73396 |
Sterimol/B4: 7.00981 | Sterimol/L: 17.5326 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 690.303 | Positive charged surface: 409.548 | Negative charged surface: 280.755 | Volume: 404.5 |
Hydrophobic surface: 561.749 | Hydrophilic surface: 128.554 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |