Physical Properties | | | |
Molecular Weight: 386.452 g/mol | logS: -4.69004 | SlogP: 2.50994 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.00494247 | Sterimol/B1: 2.37866 | Sterimol/B2: 2.38047 | Sterimol/B3: 2.52833 |
Sterimol/B4: 9.21336 | Sterimol/L: 22.2457 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 723.273 | Positive charged surface: 529.385 | Negative charged surface: 193.888 | Volume: 372.875 |
Hydrophobic surface: 468.693 | Hydrophilic surface: 254.58 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 4 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |