Physical Properties | | | |
Molecular Weight: 409.442 g/mol | logS: -2.88408 | SlogP: 2.1036 | Reactive groups: 1 |
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Topological Properties | | | |
Globularity: 0.219743 | Sterimol/B1: 2.2844 | Sterimol/B2: 3.62294 | Sterimol/B3: 7.46393 |
Sterimol/B4: 10.6561 | Sterimol/L: 15.6875 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 685.243 | Positive charged surface: 502.019 | Negative charged surface: 183.224 | Volume: 385.875 |
Hydrophobic surface: 518.96 | Hydrophilic surface: 166.283 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 1 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |