Physical Properties | | | |
Molecular Weight: 371.433 g/mol | logS: -3.98796 | SlogP: 3.15497 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0795712 | Sterimol/B1: 2.1947 | Sterimol/B2: 3.43524 | Sterimol/B3: 3.67798 |
Sterimol/B4: 10.2004 | Sterimol/L: 14.3654 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 600.139 | Positive charged surface: 518.641 | Negative charged surface: 75.4158 | Volume: 352.125 |
Hydrophobic surface: 532.994 | Hydrophilic surface: 67.145 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 1 | Hydrogen bond acceptors: 6 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 2 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |