Physical Properties | | | |
Molecular Weight: 408.462 g/mol | logS: -4.03266 | SlogP: 3.2538 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0836689 | Sterimol/B1: 3.54354 | Sterimol/B2: 4.06751 | Sterimol/B3: 5.23559 |
Sterimol/B4: 6.19783 | Sterimol/L: 19.6637 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 680.139 | Positive charged surface: 420.771 | Negative charged surface: 254.197 | Volume: 381.75 |
Hydrophobic surface: 491.646 | Hydrophilic surface: 188.493 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 2 | Hydrogen bond acceptors: 2 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |