Physical Properties | | | |
Molecular Weight: 417.339 g/mol | logS: -8.4477 | SlogP: 7.40177 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.127698 | Sterimol/B1: 2.42089 | Sterimol/B2: 2.93837 | Sterimol/B3: 4.80998 |
Sterimol/B4: 11.4661 | Sterimol/L: 16.1487 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 662.808 | Positive charged surface: 291.599 | Negative charged surface: 360.122 | Volume: 387.5 |
Hydrophobic surface: 636.777 | Hydrophilic surface: 26.031 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 0 | Hydrogen bond acceptors: 1 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 0 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 1 | Oprea's lead like rule: 0 | |