Physical Properties | | | |
Molecular Weight: 224.26 g/mol | logS: -0.38748 | SlogP: -0.9087 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.107766 | Sterimol/B1: 2.21947 | Sterimol/B2: 3.60614 | Sterimol/B3: 4.13557 |
Sterimol/B4: 5.30761 | Sterimol/L: 12.6984 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 430.999 | Positive charged surface: 298.87 | Negative charged surface: 132.129 | Volume: 212.375 |
Hydrophobic surface: 222.058 | Hydrophilic surface: 208.941 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 5 | Hydrogen bond acceptors: 4 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |