Physical Properties | | | |
Molecular Weight: 353.589 g/mol | logS: -4.06779 | SlogP: 1.7035 | Reactive groups: 0 |
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Topological Properties | | | |
Globularity: 0.0948263 | Sterimol/B1: 2.79391 | Sterimol/B2: 3.53253 | Sterimol/B3: 4.18842 |
Sterimol/B4: 5.69881 | Sterimol/L: 13.6305 | | | |
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Surface and Volume Properties | | | |
Accessible surface: 512.89 | Positive charged surface: 228.106 | Negative charged surface: 284.784 | Volume: 267.5 |
Hydrophobic surface: 336.255 | Hydrophilic surface: 176.635 | | |
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Pharmacophoric Properties | | | |
Hydrogen bond donors: 3 | Hydrogen bond acceptors: 5 | Acid groups: 0 | Basic groups: 0 |
Chiral centers: 4 | | | |
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Drug- and Lead-like Properties | | | |
Lipinski's drug-like rule: 1 | Violations of Lipinski's rule: 0 | Oprea's lead like rule: 1 | |